Anti-Human ICOS/CD278 Rabbit Recombinant Antibody proteintech 98214-1-RR
$59.00
In stock
SKU
98214-1-RR
ICOS, CVID1, CD278, AILIM, Activation-inducible lymphocyte immunomediatory molecule
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: inducible T-cell co-stimulator |
| Applications: FC | Observed Molecular Weight: BC028210 |
| Formulation: PBS, Azide | GenBank Accession Number: 29851 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purfication |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Q9Y6W8 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation, and lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13. |