Caspase 1 Polyclonal antibody proteintech 31020-1-AP
$449.00
In stock
SKU
31020-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Mouse, Rat And More (1) | Immunogen: CatNo: Ag34441 Product name: Recombinant mouse Casp1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 119-296 aa of BC008152 Sequence: DNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFK Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 35-40 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Caspase 1 |
| Conjugate: Unconjugated | Gene Symbol: 12362 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3669817 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Mouse, Rat | Form: Antigen affinity Purification |
| Host / Isotype: Rabbit / IgG | Background Information: CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). 31020-1-AP is designed for mouse caspase 1. |
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