ATP1A1/2/3/4 Recombinant monoclonal antibody proteintech 84999-4-RR
$449.00
In stock
SKU
84999-4-RR
ATP1A2, 242414G12, alpha 2 ATPase, ATP1A 2, EC:7.2.2.13
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 97-100 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ATP1A2 |
| Conjugate: Unconjugated | Gene Symbol: 477 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: P50993 |
| Host / Isotype: Recombinant | Background Information: ATP1A2 (Na+/K+-ATPase α-2 subunit) is the catalytic component of the active enzyme Na+/K+-ATPase, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. The Na+/K+-ATPase is composed of a larger catalytic α-subunit (~110 kDa) and a small β-subunit (~55 kDa). The α subunit has four isoforms identified to date: α1, α2, α3 and α4. The α1 isoform is expressed ubiquitously but the α2 isoform is present largely in the skeletal muscle, heart and vascular smooth muscle. The α3 isoform is found almost exclusively in neurons and ovaries. The α4 isoform is expressed in sperm. This antibody can recognizes all the isoforms of α subunit. For optimal WB detection with ATP1A2, we do not recommend boiling the sample after lysis. |