KAP1 Monoclonal antibody proteintech 66630-1-Ig

$449.00
In stock
SKU
66630-1-Ig

 

TRIM28, 1B9G12, E3 SUMO-protein ligase TRIM28, EC:2.3.2.27, KAP 1

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human And More (2) Immunogen: CatNo: Ag7519 Product name: Recombinant human KAP1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 484-835 aa of BC004978 Sequence: KVPRVSLERLDLDLTADSQPPVFKVFPGSTTEDYNLIVIERGAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALAEGPGAEGPRLASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAFGDTKFSAVLVEPPPMSLPGAGLSSQELSGGPGDGP Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ChIP, ELISA Observed Molecular Weight: 89 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC004978
Conjugate: Unconjugated Gene Symbol: KAP1
Tested Applications: Positive WB detected in Gene ID (NCBI): 10155
Application: Western Blot (WB) RRID: AB_2732886
Dilution: WB : 1:20000-1:100000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: KAP1, also named as TRIM28 or RNF96, is a 835 amino acid protein, which contain one RING-type zinc finger, one PHD-type zinc finger, one bromo domain and two B box-type zinc fingers. KAP1 localizes in the nucleus and Belongs to the TRIM/RBCC family. KAP1 is a nuclear corepressor for KRAB domain-containing zinc finger proteins and mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 to the promoter regions of KRAB target genes. KAP1 is expressed in all tissues tested including spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. The calcualted molecular weight of KAP1 is 89 kDa, but modified KAP1 is about 100 kDa. (PMID: 18590578 )

 

 

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