CAPN3 Monoclonal antibody proteintech 67366-1-Ig

$449.00
In stock
SKU
67366-1-Ig

 

1G12A5, Calcium-activated neutral proteinase 3, Calpain 3, calpain 3, (p94), Calpain L3

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat, pig Immunogen: CatNo: Ag13179 Product name: Recombinant human CAPN3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-156 aa of BC004883 Sequence: MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 18 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC004883
Conjugate: Unconjugated Gene Symbol: CAPN3
Tested Applications: Positive WB detected in Gene ID (NCBI): 825
Application: Western Blot (WB) RRID: AB_2882618
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Calpain 3 (CAPN3), a major intracellular protease, is a muscle-specific member of the calpain large subunit family that specifically binds to titin. CAPN3 plays a role in the dysferlin protein complex and that disruption of CAPN3 function may affect muscle membrane repair and remodeling. CAPN3 has some isoforms with MW of 94, 84, 93, 36, 18 kDa. CAPN3 autolysis generates a small N-terminal fragment of 34 kDa and a large C-terminal fragment whose size ranges from 55 to 60 kDa during self-processing (PMID: 9794799, 14645524).

 

 

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