KIF5B Polyclonal antibody proteintech 21632-1-AP
$449.00
In stock
SKU
21632-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (2) | Immunogen: CatNo: Ag16250 Product name: Recombinant human KIF5B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 662-782 aa of BC126279 Sequence: ESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDL Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA | Observed Molecular Weight: 963 aa, 110 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC126279 |
| Conjugate: Unconjugated | Gene Symbol: KIF5B |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3799 |
| Application: Western Blot (WB) | RRID: AB_11182931 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: KIF5B, also known as KINH, KNS1, belongs to the Kinesin-1 family. KIF5B contains three structural domains: a globular N-terminal motor domain, a central alpha-helical rod domain, and a globular C-terminal domain. During the G2 phase of the cell cycle in a BICD2-dependent manner, KIF5B antagonizes the dynein function and drives the separation of nuclei and centrosomes (PMID: 20386726). KIF5B drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (KIF5B:24088571). |
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