Anti-Human CEACAM5/8 (CD66b/e) Rabbit Recombinant Antibody proteintech 98012-1-RR
$84.00
In stock
SKU
98012-1-RR
CD66e, CEACAM5, CEACAM5/CD66e, CEACAM8/CD66b, CD66b
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CEACAM5/8 (CD66b/e) |
| Applications: FC | |
| Formulation: PBS, Azide | GenBank Accession Number: Unconjugated |
| Conjugate: Unconjugated | Gene Symbol: Liquid |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Protein A purification |
| Application: Flow Cytometry (FC) | RRID: P31997 |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: PBS with 0.09% sodium azide, pH 7.3. |
| Tested Reactivity: Human | Form: Store at 2-8°C. Stable for one year after shipment. |
| Host / Isotype: Recombinant | Background Information: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e mainly serves as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEACAM8, also known as CD66b, CGM6 or NCA-95, is a glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on granulocytes and is involved in regulating adhesion and activation of eosinophils (PMID: 8104998; 18056392; 18056392). This antibody is raised against 35-319 aa of human CEACAM8/CD66b and can cross-react with CEACAM5/CD66e. |
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