Anti-Human CD18 (TS1/18) Mouse IgG2a Recombinant Antibody proteintech 65595-1-MR
$67.00
In stock
SKU
65595-1-MR
ITGB2, LCAMB, LAD, Integrin beta-2, Integrin beta 2
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| Applications: FC | Observed Molecular Weight: BC005861 |
| Formulation: PBS, Azide | GenBank Accession Number: 3689 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000160255 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670343 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570). |
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