RNASEH1 Recombinant monoclonal antibody proteintech 82771-1-RR
$449.00
In stock
SKU
82771-1-RR
RNH1, RNASEH 1, RNase H1, EC:3.1.26.4, 2C12
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: ribonuclease H1 |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 32 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: RNASEH1 |
| Conjugate: Unconjugated | Gene Symbol: 246243 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086532 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Ribonucleases H are enzymes that cleave the RNA of RNA/DNA hybrids that form during replication and repair and which could lead to DNA instability if they were not processed. Eukaryotic RNases H are larger and more complex than their prokaryotic counterparts [PMID:12667461]. Eukaryotic RNase H1 has acquired a Hybrid Binding Domain that confers processivity and affinity for the substrate. Because of its essential role and its similarities in structure and enzymatic mechanism to the RNase H of HIV reverse transcriptase, RNASEH1 has been implicated in mitochondrial DNA replication during mouse development [PMID:19228196]. |
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