VAMP8 Recombinant monoclonal antibody proteintech 85400-4-RR
$449.00
In stock
SKU
85400-4-RR
VAMP-8, 242830B11, EDB, Endobrevin, VAMP 8
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: vesicle-associated membrane protein 8 (endobrevin) |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 15 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: VAMP8 |
| Conjugate: Unconjugated | Gene Symbol: 8673 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: Q9BV40 |
| Host / Isotype: Recombinant | Background Information: VAMP8, also named as endobrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE (soluble NSF-attachment protein receptor) superfamily. Characterized by a common sequence called the SNARE motif, SNARE proteins are involved in membrane fusion and vesicular transport (PMID: 11252968). VAMP8 is involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. It is required for dense-granule secretion in platelets and plays a role in regulated enzyme secretion in pancreatic acinar cells. VAMP8 is also involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. |
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