MYB/c-Myb Recombinant monoclonal antibody proteintech 82804-2-RR
$449.00
In stock
SKU
82804-2-RR
MYB, c-Myb, Transcriptional activator Myb, Proto-oncogene c-Myb, Proto oncogene c Myb
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: v-myb myeloblastosis viral oncogene homolog (avian) |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 40-50 kDa, 72-80 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: c-Myb |
| Conjugate: Unconjugated | Gene Symbol: 4602 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670557 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: The MYB protein is a transcription factor that plays a key role in regulating the proliferation/differentiation of progenitor cells in bone marrow, colonic crypts, and neurogenic niches [PMID:18574464]. It is involved in the regulation of epithelial-to-mesenchymal transition (EMT) and invasion in neuroblastoma, colon carcinoma, and embryonic kidney cells through the upregulation of the transcription repressor Slug [PMID:20622260]. It also a DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3', and plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. MYB exists some isoforms with MV 85, 75, 72, 68, 63 and 40 kDa. |
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