MOV10 Recombinant monoclonal antibody proteintech 85818-5-RR
$449.00
In stock
SKU
85818-5-RR
Armitage homolog, EC:3.6.4.13, fSAP113, gb110, Helicase MOV-10
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: Mov10, Moloney leukemia virus 10, homolog (mouse) |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 115 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MOV10 |
| Conjugate: Unconjugated | Gene Symbol: 4343 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: Q9HCE1 |
| Host / Isotype: Recombinant | Background Information: MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retrotransposition of endogenous retroelements in mammals (PMID:22727223). MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages (PMID:20215113). It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA. |
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