KDM3A/JMJD1A Recombinant monoclonal antibody proteintech 83571-2-RR
$449.00
In stock
SKU
83571-2-RR
KDM3A, KDM3A,JMJD1A, JmjC domain-containing histone demethylation protein 2A, JHMD2A, JHDM2A
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: lysine (K)-specific demethylase 3A |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 140-150 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: KDM3A/JMJD1A |
| Conjugate: Unconjugated | Gene Symbol: 55818 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671184 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: KDM3A, also name as JMJD1A, JHDM2A, JMJD1, JMJD1A, KIAA0742 and TSGA, belongs to the JHDM2 histone demethylase family. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It is involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. It is involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. (PubMed:16603237), JMJD1A is a useful biomarker for hypoxic tumor cells and a prognostic marker that could be a promising therapeutic target against CRC. |
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