CD40L/CD154 Recombinant monoclonal antibody proteintech 83884-3-RR
$449.00
In stock
SKU
83884-3-RR
CD154, Cd40l, 240743F5, CD40 ligand, Cd40lg
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: CD40 ligand |
| Applications: WB, ELISA | Observed Molecular Weight: 32 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD154 |
| Conjugate: Unconjugated | Gene Symbol: 21947 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671466 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:18000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or an 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis. |
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