RIG-1/DDX58 Polyclonal antibody proteintech 20566-1-AP
$449.00
In stock
SKU
20566-1-AP
DDX58, RIG-I, Retinoic acid-inducible gene 1 protein, EC:3.6.4.13, DEAD box protein 58
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, RIP, ELISA | Observed Molecular Weight: 106 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_014314 |
| Conjugate: Unconjugated | Gene Symbol: RIG-1/DDX58 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 23586 |
| Application: Western Blot (WB) | RRID: AB_10700006 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: DDX58, also named as RIG-1, belongs to the helicase family. It is involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). It is essential for the production of interferons in response to RNA viruses including paramyxoviruses, influenza viruses, Japanese encephalitis virus and HCV. The antibody is specific to DDX58. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
