CD200 Recombinant monoclonal antibody proteintech 83437-5-RR
$449.00
In stock
SKU
83437-5-RR
OX2, Mox2, CD200 antigen, 240391A8
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: CD200 antigen |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 40 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Cd200 |
| Conjugate: Unconjugated | Gene Symbol: 17470 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671078 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332). |
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