OLR1/LOX1 Polyclonal antibody proteintech 11837-1-AP

$449.00
In stock
SKU
11837-1-AP

 

OLR1, CLEC8A, C-type lectin domain family 8 member A, hLOX 1, hLOX1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse Immunogen: CatNo: Ag2437 Product name: Recombinant human OLR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-273 aa of BC022295 Sequence: MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ Predict reactive species
 Applications: WB, IHC, IF, IP, CoIP, ELISA Observed Molecular Weight: 273 aa, 31 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC022295
Conjugate: Unconjugated Gene Symbol: OLR1
Tested Applications: Positive WB detected in Gene ID (NCBI): 4973
Application: Western Blot (WB) RRID: AB_2299037
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: OLR1/LOX-1 acts as a receptor, in the form of homodimer, that mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein (oxLDL) (PMID: 9052782, 15695803). ORL1 is predominantly expressed in endothelial cells and vascular-rich organs such as the placenta, lung, liver, and brain (PMID: 9828121). OLR1 is a protein containing 273 amino acids with a calculated molecular mass of 31 kDa but an apparent molecular mass of 50 kDa, which may result from the glycosylation of four potential N-linked glycosylation sites located at the C-terminal domain (PMID: 9052782).

 

 

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