CD107b / LAMP2 Recombinant monoclonal antibody proteintech 84474-5-RR
$449.00
In stock
SKU
84474-5-RR
CD107b, Lamp2, 241893A7, Lamp 2, Mac3
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: lysosomal-associated membrane protein 2 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 90-110 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD107b / LAMP2 |
| Conjugate: Unconjugated | Gene Symbol: 16784 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Mouse | Form: P17047-1 |
| Host / Isotype: Recombinant | Background Information: LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697). |
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