PHGDH Recombinant monoclonal antibody proteintech 81986-1-RR
$449.00
In stock
SKU
81986-1-RR
3 PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, PGDH3, PHGDH, phosphoglycerate dehydrogenase, SERA
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: Human, mouse, rat | Immunogen: phosphoglycerate dehydrogenase |
| Applications: WB, IP, IHC, ELISA | Observed Molecular Weight: 57 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PHGDH |
| Conjugate: Unconjugated | Gene Symbol: 26227 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2935595 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: PHGDH(D-3-phosphoglycerate dehydrogenase) is also named as 3-PGDH, PGDH3 and belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. 3-PGDH deficiency is a rare recessive inborn error in the biosynthesis of the amino acid L-serine characterized clinically by congenital microcephaly, psychomotor retardation, and intractable seizures(PMID:19235232 ). |
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