TFF2 Recombinant monoclonal antibody proteintech 83717-4-RR

$449.00
In stock
SKU
83717-4-RR

 

SML1, 240661G12, SP, Spasmolysin, Spasmolytic polypeptide

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: trefoil factor 2
 Applications: WB, FC (Intra), IP, ELISA Observed Molecular Weight: 18-20 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: TFF2
Conjugate: Unconjugated Gene Symbol: 7032
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671319
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein A purfication
Host / Isotype: Recombinant Background Information: The trefoil factor family (TFF), comprises of three polypeptides, TFF1, TFF2 and TFF3 (7-12 kDa), secreted to mucosal surfaces by mucus producing cells, prominently in the gastrointestinal tract. TFF2, also known as spasmolytic polypeptide, is a low-molecular weight protein, expressed in mucous neck cells of the fundus and glands at the base of the antrum in normal human stomach. TFF2 could Inhibit gastrointestinal motility and gastric acid secretion. However, recent studies suggest that TFF2 could also play an important role in the immune system. We got a 18-20 kDa band in western botting maybe due to glycosylatation, and mature TFF2 is a 12 kDa protein (PMID: 10716671).

 

 

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