CPNE3 Recombinant monoclonal antibody proteintech 83820-5-RR
$449.00
In stock
SKU
83820-5-RR
240871E5, Copine 3, Copine III, Copine-3, copineIII
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: copine III |
| Applications: WB, IF/ICC, FC (Intra), IP, ELISA | Observed Molecular Weight: 60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CPNE3 |
| Conjugate: Unconjugated | Gene Symbol: 8895 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671405 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:14000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Copines are a family of evolutionarily conserved calcium-dependent phospholipid-binding proteins (PMID: 9430674). They contain two Ca(2+)- and phospholipid-binding domains known as C2 domains. Copines are potentially involved in regulating membrane trafficking and in protein-protein interactions. Copine III (CPNE3) has also been identified as a ligand of ERBB2 and plays an important role in various carcinogenesis. The high expression of CPNE3 is an adverse prognostic biomarker for acute myeloid leukemia (PMID: 28670859). |