BAG6 Monoclonal antibody proteintech 66661-1-Ig
$449.00
In stock
SKU
66661-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag24525 Product name: Recombinant human BAG6 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 1-184 aa of BC003133 Sequence: MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRME Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 119 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC003133 |
| Conjugate: Unconjugated | Gene Symbol: BAT3/BAG-6 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7917 |
| Application: Western Blot (WB) | RRID: AB_2858188 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: BAT3 also known as Scythe or BAG6, is a nuclear protein implicated in the control of apoptosis and natural killer (NK) cell-dendritic cell (DC) interaction. BAT3 was first discovered as a member of a group of genes located within the class III region of the human major histocompatibility complex on chromosome 6, and has been extensively studied for its role in regulating apoptosis under various stress conditions such as DNA damage and endoplasmic reticulum-related stress. BAT3 has been shown to be required for p53 acetylation, which is critical for the enhancement of p53 transcriptional activity in response to DNA damage. In addition, BAT3 is involved in the regulation of development and reproduction of mammals by acting as a co-chaperone of the heat shock protein HSP70. |