Phospho-JNK (Thr183/Tyr185) Monoclonal antibody proteintech 60666-1-Ig
$449.00
In stock
SKU
60666-1-Ig
JNK (Thr183/Tyr185), Phospho-JNK, phospho-JNK(Thr183/Tyr185), phospho‐JNK/SAPK (Thr183/Tyr185), phospho-JNK1/2 (Thr183/Tyr185)
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: Human, Mouse, Rat And More (1) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 48 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_138982 |
| Conjugate: Unconjugated | Gene Symbol: JNK |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5599 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Mouse / IgG2b | Background Information: MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. The JNK gene generates 10 forms of JNK through alternative splicing, and the protein encoded by the JNK gene has or does not have a COOH terminal, resulting in 46 kDa and 54 kDa proteins. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. The antibody can detect endogenous levels of p46 and p54 SAPK/JNK when phosphorylated at Thr183 and Tyr185. It will also react with JNK singly phosphorylated at Thr183. |
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