SP1 Polyclonal antibody proteintech 21962-1-AP
$449.00
In stock
SKU
21962-1-AP
SP 1, Sp1 transcription factor, Specificity protein 1, TSFP1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat, Monkey And More (2) | Immunogen: CatNo: Ag16720 Product name: Recombinant human SP1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 437-785 aa of BC062539 Sequence: NLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGRRTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCTWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKGGPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQVADLQSINISGNGF Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ChIP, ELISA | Observed Molecular Weight: 785 aa, 81 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC062539 |
| Conjugate: Unconjugated | Gene Symbol: SP1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6667 |
| Application: Western Blot (WB) | RRID: ENSG00000185591 |
| Dilution: WB : 1:2000-1:16000 | Conjugate: AB_10898171 |
| Tested Reactivity: Human, Mouse, Rat, Monkey | Form: Unconjugated |
| Host / Isotype: Rabbit / IgG | Background Information: The transcription factor Sp1 is a C2H2 zinc-finger protein that is involved in the regulation of a wide variety of genes, including housekeeping genes and tumor-developing genes. It is associated with tumor development, growth, and metastasis [PMID: 16209919]. It regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Besides, it has a role in modulating the cellular response to DNA damage, recruiting SMARCA4/BRG1 on the c-FOS promoter, regulation of FE65 gene expression [PMID:11371615,16332679]. SP1 is detected with MW 95-105 kDa and 65 kDa in this paper(PMID: 10618488). |
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