WNT2 Monoclonal antibody proteintech 66656-1-Ig

$449.00
In stock
SKU
66656-1-Ig

 

3H7B10, Int 1 like protein 1, Int 1 related protein, INT1L1, Int-1-like protein 1

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag25185 Product name: Recombinant human WNT2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-360 aa of BC029854 Sequence: MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTAT Predict reactive species
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 40 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC029854
Conjugate: Unconjugated Gene Symbol: WNT2
Tested Applications: Positive WB detected in Gene ID (NCBI): 7472
Application: Western Blot (WB) RRID: AB_2882013
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Wnt2 is a secreted glycoprotein that is one of the canonical Wnt ligands. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt2 is known to directly regulate β-catenin activity, the key player in proliferation and inflammation. Recently, studies have demonstrated that Wnt2 is overexpressed in various human cancers, including esophageal, gastric, colorectal, breast, lung, cervical, and malignant glioma.

 

 

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