U2AF35 Monoclonal antibody proteintech 60289-1-Ig

$449.00
In stock
SKU
60289-1-Ig

 

U2AF1, U2AFBP, RNU2AF1, RN, FP793

Host / Isotype: Mouse / IgG2c Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag0399 Product name: Recombinant human U2AF35 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 26-240 aa of BC001923 Sequence: ACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), IP, ELISA Observed Molecular Weight: 28 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001923
Conjugate: Unconjugated Gene Symbol: U2AF1
Tested Applications: Positive WB detected in Gene ID (NCBI): 7307
Application: Western Blot (WB) RRID: AB_2858277
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG2c Background Information: U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder. The calculated molecular weight of U2AF35 is 28 kDa, but the modified U2AF35 protein is about 35-40 kDa.

 

 

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