Endoglin/CD105 Monoclonal antibody proteintech 67075-1-Ig
$449.00
In stock
SKU
67075-1-Ig
CD105, 2D5E8, END, Endoglin, ENG
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: Human And More (3) | Immunogen: CatNo: Ag27837 Product name: Recombinant human Endoglin/CD105 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 33-221 aa of BC014271 Sequence: QPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHIL Predict reactive species |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 71 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC014271 |
| Conjugate: Unconjugated | Gene Symbol: CD105 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2022 |
| Application: Western Blot (WB) | RRID: AB_2882383 |
| Dilution: WB : 1:5000-1:20000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481) |
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