TLE3 Monoclonal antibody proteintech 66083-1-Ig
$449.00
In stock
SKU
66083-1-Ig
1D11A8, Enhancer of split groucho-like protein 3, ESG, ESG3, GRG 3
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: human | Immunogen: transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| Applications: WB, IHC, IP, ELISA | Observed Molecular Weight: 90 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TLE3 |
| Conjugate: Unconjugated | Gene Symbol: 7090 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_11182267 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: TLE3, also named as KIAA1547 and ESG3, belongs to the WD repeat Groucho/TLE family. It is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE3 is a member of the transducin-like enhancer of split (TLE) family of proteins that have been implicated in the tumorgenesis and classification of sarcomas. It is a candidate biomarker of response to taxane therapy.(PMID:19309506 ) |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
