PI3 Kinase p85 Alpha Monoclonal antibody proteintech 60225-1-Ig

$449.00
In stock
SKU
60225-1-Ig

 

P85a; PIK3R1, PI3K p85 alpha, PI3K p85 α, PIK3R1, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human, Mouse, Rat, Pig, Rabbit And More (3) Immunogen: CatNo: Ag2344 Product name: Recombinant human P85a; PIK3R1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 78-454 aa of BC030815 Sequence: RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR Predict reactive species
 Applications: WB, IHC, IF, IP, CoIP, ELISA Observed Molecular Weight: 85 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC030815
Conjugate: Unconjugated Gene Symbol: PI3 Kinase p85 Alpha
Tested Applications: Positive WB detected in Gene ID (NCBI): 5295
Application: Western Blot (WB) RRID: AB_11042594
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig, Rabbit Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of INS and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.

 

 

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