METTL3 Polyclonal antibody proteintech 15073-1-AP

$449.00
In stock
SKU
15073-1-AP

 

EC:2.1.1.348, hMETTL3, Methyltransferase-like protein 3, MT A70, MTA70

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat, Monkey And More (6) Immunogen: CatNo: Ag7110 Product name: Recombinant human METTL3 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 229-580 aa of BC001650 Sequence: LNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, IP, CoIP, ChIP, RIP, ELISA Observed Molecular Weight: 64 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001650
Conjugate: Unconjugated Gene Symbol: METTL3
Tested Applications: Positive WB detected in Gene ID (NCBI): 56339
Application: Western Blot (WB) RRID: AB_2142033
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Monkey Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: METTL3 is a key S-adenosyl-L-methionine-binding subunit, which is a component of a complex multicomponent enzyme that catalyzes the methylation of internal adenosine residues in eukaryotic mRNA, forming N6-methyladenosine. It contains 2 putative nuclear localization signals and 2 consensus methylation motifs. The calculated molecular weight of METTL3 is 64 kDa, but modified METTL3 is about 65-70 kDa.

 

 

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