DRD1 Polyclonal antibody proteintech 17934-1-AP

$449.00
In stock
SKU
17934-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag12366 Product name: Recombinant human DRD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 338-446 aa of BC074978 Sequence: RKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT Predict reactive species
 Applications: WB, IF-Fro, ELISA Observed Molecular Weight: 446 aa, 49 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC074978
Conjugate: Unconjugated Gene Symbol: DRD1
Tested Applications: Positive WB detected in Gene ID (NCBI): 1812
Application: Western Blot (WB) RRID: AB_10598308
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Dopamine is a neurotransmitter that plays a crucial role in physical and mental health, such as cardiovascular, hormonal, renal, and central nervous systems (PMID: 29220802). Five subtypes of mammalian dopamine receptors are grouped into two classes, the D1- and D2-like classes. The D1-like class includes D1 and D5 receptors whereas the D2-like class includes D2, D3, D4 subtypes (PMID: 9457173). Dopamine receptor D1 (DRD1) is the most abundant form of dopamine receptor in the central nervous system. DRD1 stimulates adenylate cyclase, modulates D2 receptor activity, regulates neuron growth and differentiation, and mediates several behavioral responses (PMID: 1977312). DRD1 has a calculated molecular weight of 49 kDa, larger apparent molecular weight of 60-80 kDa may be due to glycosylation (PMID: 1281547; 23821371).

 

 

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