Anti-Mouse Foxp3 (3G3) Proteintech 65089-1-Ig
$299.00
In stock
SKU
65089-1-Ig
Foxp3, JM2, scurfin, sf, 3G3, forkhead box P3
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Immunohistochemistry (IHC) | Formulation:：PBS, Azide2 |
| Reactivity：Mouse | Formulation:：PBS, Azide3 |
| Type：Antibody | Formulation:：PBS, Azide4 |
| RRID：20371 | Formulation:：PBS, Azide5 |
| Storage Buffer：Affinity purification | Formulation:：PBS, Azide6 |
| Background Information：Foxp3 (forkhead box P3), also named as IPEX, JM2 and scurfin, is a member of the forkhead transcription factor family and is essential for normal immune homeostasis (PMID: 11138001; 20429413). Foxp3 is specifically expressed in CD4+ CD25+ regulatory T cells and is crucial for their development and suppressive activity (PMID: 12612578; 12612581). In scurfy mouse, disruption of Foxp3 results in the fatal lymphoproliferative disorder attributed to the lack of an immune-suppressive component in the immune system (PMID: 25683611; 11138001). Similar to mice, genetic defects in human Foxp3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) which also known as X-linked autoimmunity-immunodeficiency syndrome (PMID: 11137993). | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Immunohistochemistry (IHC)0 |
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