Beta Catenin Polyclonal antibody Proteintech 51067-2-AP
$299.00
In stock
SKU
51067-2-AP
b cat, B-catenin, beta-Catenin, Catenin beta 1, Catenin beta-1
| Formulation::PBS, Azide, Glycerol | Formulation::PBS, Azide, Glycerol1 |
| Applications:Western Blot (WB) | Formulation::PBS, Azide, Glycerol2 |
| Reactivity:Human, Mouse, Rat, Pig, Canine, Chicken, Zebrafish, Hamster, Sheep, Goat | Formulation::PBS, Azide, Glycerol3 |
| Type:Antibody | Formulation::PBS, Azide, Glycerol4 |
| RRID:BC058926 | Formulation::PBS, Azide, Glycerol5 |
| Storage Buffer:AB_2086128 | Formulation::PBS, Azide, Glycerol6 |
| Background Information:β-Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. β-Catenin is a 92-kDa protein, originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, β-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/β-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of β-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222) | Formulation::PBS, Azide, Glycerol7 |
| biogegep8 | Formulation::PBS, Azide, Glycerol8 |
| biogegep9 | Formulation::PBS, Azide, Glycerol9 |
| Formulation::PBS, Azide, Glycerol0 | Applications:Western Blot (WB)0 |