FcZero-rAb? APC Anti-Human CD80 Rabbit Recombinant Antibody Proteintech APC-FcA98384
$299.00
In stock
SKU
APC-FcA98384
Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1
| Formulation::PBS, Azide, BSA | Formulation::PBS, Azide, BSA1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide, BSA2 |
| Reactivity:Rabbit / IgG | Formulation::PBS, Azide, BSA3 |
| Type:CatNo: Eg3505 Product name: Recombinant Human CD80/B7-1 protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 35-242 aa of NM_005191 Sequence: VIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDN Predict reactive species | Formulation::PBS, Azide, BSA4 |
| RRID:941 | Formulation::PBS, Azide, BSA5 |
| Storage Buffer:Protein A purification | Formulation::PBS, Azide, BSA6 |
| Background Information:CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215) | Formulation::PBS, Azide, BSA7 |
| biogegep8 | Formulation::PBS, Azide, BSA8 |
| biogegep9 | Formulation::PBS, Azide, BSA9 |
| Formulation::PBS, Azide, BSA0 | Applications:Flow Cytometry (FC)0 |