AHR Polyclonal antibody proteintech 28727-1-AP

$449.00
In stock
SKU
28727-1-AP

 

Class E basic helix-loop-helix protein 76, bHLHe76, Ah receptor

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (1) Immunogen: CatNo: Ag28935 Product name: Recombinant human AHR protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 25-300 aa of BC070080 Sequence: PIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ChIP, ELISA Observed Molecular Weight: 848 aa, 96 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC070080
Conjugate: Unconjugated Gene Symbol: AHR
Tested Applications: Positive WB detected in Gene ID (NCBI): 196
Application: Western Blot (WB) RRID: AB_2918196
Dilution: WB : 1:1000-1:3000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter. AHR calculated molecular masses differ by

 

 

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