RPL11 Polyclonal antibody proteintech 16277-1-AP

$449.00
In stock
SKU
16277-1-AP

 

60S ribosomal protein L11, CLL associated antigen KW 12, CLL-associated antigen KW-12, DBA7, GIG34

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag9356 Product name: Recombinant human RPL11 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-177 aa of BC018970 Sequence: MADQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 177 aa, 20 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC018970
Conjugate: Unconjugated Gene Symbol: RPL11
Tested Applications: Positive WB detected in Gene ID (NCBI): 6135
Application: Western Blot (WB) RRID: AB_2181292
Dilution: WB : 1:1000-1:8000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibit 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.

 

 

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