GPT2 Polyclonal antibody proteintech 16757-1-AP

$449.00
In stock
SKU
16757-1-AP

 

Alanine aminotransferase 2, ALAT2, ALT2, EC:2.6.1.2, Glutamic--alanine transaminase 2

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag10273 Product name: Recombinant human GPT2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 174-523 aa of BC062555 Sequence: VPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), IP, ELISA Observed Molecular Weight: 523 aa, 58 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC062555
Conjugate: Unconjugated Gene Symbol: GPT2
Tested Applications: Positive WB detected in Gene ID (NCBI): 84706
Application: Western Blot (WB) RRID: AB_2112098
Dilution: WB : 1:500-1:3000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: GPT2 (Alanine aminotransferase 2; ALT2) is a key enzyme in intermediatary metabolism, catalysing the reversible transfer of the amino group of glutamate to pyruvate, yielding alanine and ketoglutarate. GPT2 protein localizes to mitochondria, and is mainly expressed in the pancreas, brain, adrenal gland, skeletal muscle and heart. Serum GPT2 is a useful marker for liver damage. Recently mutation of GPT2 has been reported to be a cause of neural disorder (27601654). 16757-1-AP antibody recognizes two different isoforms of GPT2 protein.

 

 

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