S1PR1/EDG1 Polyclonal antibody proteintech 55133-1-AP
$449.00
In stock
SKU
55133-1-AP
S1PR1, EDG1, EDG 1, ECGF1, D1S3362
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, IP, ELISA | Observed Molecular Weight: 43 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001400 |
| Conjugate: Unconjugated | Gene Symbol: S1PR1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1901 |
| Application: Western Blot (WB) | RRID: AB_10793721 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: S1PR1 (sphingosine-1-phosphate receptor 1), also known as S1P1 or EDG1, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P) (PMID: 18787560). S1P1 and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR1 is widely expressed in various cell types, including endothelial cells and lymphocytes (PMID: 14737169). S1P-S1PR1 plays a major role in lymphocyte egress and chemotaxis, cell proliferation and survival, and tumor angiogenesis and metastasis (PMID: 21102457). The antibody is specific to S1PR1. |
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