Peroxiredoxin 2 Polyclonal antibody proteintech 10545-2-AP

$449.00
In stock
SKU
10545-2-AP

 

PRDX2, EC:1.11.1.24, Natural killer cell-enhancing factor B, NKEFB, NKEF-B

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag0835 Product name: Recombinant human PRDX2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-198 aa of BC003022 Sequence: MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, RIP, ELISA Observed Molecular Weight: 22 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC003022
Conjugate: Unconjugated Gene Symbol: peroxiredoxin 2
Tested Applications: Positive WB detected in Gene ID (NCBI): 7001
Application: Western Blot (WB) RRID: AB_2168202
Dilution: WB : 1:1000-1:8000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: PRDX2, also named as TSA, PRP, NKEFB and TDPX1, belongs to the ahpC/TSA family. It is known to act as an antioxidant enzyme whose main function is H2O2 reduction in cells. PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. It may play an important role in eliminating peroxides generated during metabolism. PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. PRDX2 actions may be related to the expression of NFKB and IKB.(PMID:21248284)

 

 

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