DFNA5/GSDME Polyclonal antibody proteintech 30696-1-AP
$449.00
In stock
SKU
30696-1-AP
Cleaved DFNA5, Cleaved DFNA5/GSDME, Cleaved Gasdermin E, Cleaved GSDME, Dfna5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse, rat | Immunogen: deafness, autosomal dominant 5 (human) |
| Applications: WB, ELISA | Observed Molecular Weight: 57 kDa, 35 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: DFNA5/GSDME |
| Conjugate: Unconjugated | Gene Symbol: 54722 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3669751 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Mouse, Rat | Form: Antigen affinity purification |
| Host / Isotype: Polyclonal | Background Information: DFNA5 (deafness, autosomal dominant 5), also known as GSDME or ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. 30696-1-AP can detect full-length GSDME and cleaved GSDME. |