Fas/CD95 Polyclonal antibody proteintech 13098-1-AP
$449.00
In stock
SKU
13098-1-AP
FAS, ALPS1A, APO-1, Apo-1 antigen, Apoptosis-mediating surface antigen FAS
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (3) | Immunogen: CatNo: Ag3718 Product name: Recombinant human FAS protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 156-335 aa of BC012479 Sequence: ECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV Predict reactive species |
| Applications: WB, IHC, IF, IP, CoIP, CHIP, ELISA | Observed Molecular Weight: 35-38 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC012479 |
| Conjugate: Unconjugated | Gene Symbol: Fas/CD95 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 355 |
| Application: Western Blot (WB) | RRID: AB_2278042 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation. |
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