Anti-Human MERTK Rabbit Recombinant Antibody proteintech 98604-2-RR
$166.00
In stock
SKU
98604-2-RR
c mer, EC:2.7.10.1, MER, Proto oncogene c Mer, Proto-oncogene c-Mer
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: c-mer proto-oncogene tyrosine kinase |
| Applications: FC | Observed Molecular Weight: NM_006343.3 |
| Formulation: PBS, Azide | GenBank Accession Number: 10461 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Q12866 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: MERTK (Mer tyrosine kinase), also known as RP38, c-Eyk, c-mer, and Tyro12, was first cloned from a human B lymphoblastoid expression library (PMID:8086340) and is one of the TAM (Tyro-3, Axl, and MerTK) receptor tyrosine kinase (RTK) family (PMID:23833304). Although this RTK, like others, can promote tumor cell proliferation to some extent, MERTK primarily lends tumor cells crucial survival advantages while promoting invasion, migration and metastasis, drug resistance, and, in the innate immune system, suppressing anti-tumor immunity (PMID:32417270). |
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