Anti-Human LILRB2/CD85d Rabbit Recombinant Antibody proteintech 98488-3-RR
$128.00
In stock
SKU
98488-3-RR
LILRB2, CD85 antigen-like family member D, CD85d, ILT 4, ILT4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| Applications: FC | Observed Molecular Weight: NM_005874.4 |
| Formulation: PBS, Azide | GenBank Accession Number: 10288 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Q8N423-1 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: LILRB2 (Leukocyte immunoglobulin-like receptor subfamily B member 2), also known as ILT4, CD85d or MIR10, is a type I transmembrane glycoprotein that contains four extracellular immunoglobulin domains, a transmembrane domain, and three cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (PMID: 33928233). LILRB2 is mainly expressed in immunocytes including monocytes, macrophages, and dendritic cells, and transduces negative signals by its association with SHP-1 phosphatase via the ITIMs (PMID: 35717259). LILRB2 can interact with various ligands such as HLA-A, HLA-B, HLA-C, HLA-G, HLA-F, CD1c, CD1d, angiopoietin-like proteins (ANGPTLs), and SEMA4A. |
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