Anti-Human L1CAM/CD171 Rabbit Recombinant Antibody proteintech 98130-1-RR
$166.00
In stock
SKU
98130-1-RR
L1CAM, 240978A7, CAML1, CD171, HSAS
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: L1 cell adhesion molecule |
| Applications: FC | Observed Molecular Weight: BC126229 |
| Formulation: PBS, Azide | GenBank Accession Number: 3897 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672276 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P32004 |
| Host / Isotype: Recombinant | Background Information: L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail (PMID: 3412448; 22796939). L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts (PMID: 3412448; 10767310). L1CAM is overexpressed in many human cancers and is often associated with bad prognosis (PMID: 27267927; 26111503). |
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