Anti-Human IL-15RA Rabbit Recombinant Antibody proteintech 98380-3-RR
$128.00
In stock
SKU
98380-3-RR
IL15RA, CD215, IL 15 receptor subunit alpha, IL 15R alpha, IL 15RA
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: interleukin 15 receptor, alpha |
| Applications: FC | Observed Molecular Weight: BC107777 |
| Formulation: PBS, Azide | GenBank Accession Number: 3601 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Q13261 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: Interleukin-15 (IL-15) is a pleiotropic cytokine that plays an important role in both innate and adaptive immunity. IL-15 is mainly produced by activated monocytes, macrophages and dendritic cells, and is structurally similar to IL-2 (PMID: 8178155; 12401478). These two cytokines share the same IL-2/15Rβ and common γ-chain receptor subunits. In addition, IL-2 and IL-15 have their own private α-chain receptor subunit, IL-2Rα and IL-15Rα, respectively (PMID: 7641685). The IL-15Rα chain is expressed by many cell types including monocytes, DCs, NK, T cells and fibroblasts. Several isoforms of IL-15Rα exist and are generated either by alternative splicing or by proteolytic cleavage (PMID: 10480910; 15265897). |
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