Anti-Human IL-13 Rabbit Recombinant Antibody proteintech 98159-1-RR
$72.00
In stock
SKU
98159-1-RR
IL13, 241396F3, IL 13, interleukin 13, Interleukin-13
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: interleukin 13 |
| Applications: FC (Intra) | Observed Molecular Weight: IL-13 |
| Formulation: PBS, Azide | GenBank Accession Number: AB_3672302 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC (Intra) detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) (INTRA) | RRID: Protein A purfication |
| Dilution: FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: P35225 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. IL-13 up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. IL-13 inhibits the production of a series of cytokines like IL-1, IL-6, TNF-alpha, and IL-8 by activated human monocytes. IL-13 induces IFN-gamma production by NK cells. IL-13 is thought to be important cytokine in the pathogenesis of asthma, and more recently has been shown to play a pivotal role in a number of fibrotic diseases including hepatic and pulmonary fibrosis, and nodular sclerosing Hodgkin's disease. |