Anti-Human IFN-alpha 4/IFNA4 Rabbit Recombinant Antibody proteintech 98647-1-RR
$299.00
In stock
SKU
98647-1-RR
IFNA4, IFN-alpha 4, IFN-alpha-4, IFN-α4 , Interferon alpha 4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: interferon, alpha 4 |
| Applications: FC (Intra) | Observed Molecular Weight: IFNA4 |
| Formulation: PBS, Azide | GenBank Accession Number: Unconjugated |
| Conjugate: Unconjugated | Gene Symbol: Liquid |
| Tested Applications: Positive FC (Intra) detected in | Gene ID (NCBI): Protein A purification |
| Application: Flow Cytometry (FC) (INTRA) | RRID: P05014 |
| Dilution: FC (INTRA) : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: PBS with 0.09% sodium azide, pH 7.3. |
| Tested Reactivity: Human | Form: Store at 2 - 8°C. Stable for one year after shipment. |
| Host / Isotype: Recombinant | Background Information: IFN-alpha 4 (IFN-α4 or IFNA4) belongs to the type I interferon family, a group of cytokines primarily produced in response to viral infections. As a key player in the innate immune response, IFN-α4 provides the body's first line of defense against pathogens by inducing an antiviral state in neighboring cells. Produced primarily by macrophages, IFN-α4 exerts its antiviral effects by binding to the interferon alpha receptor (IFNAR) on cell surfaces, thereby activating downstream immune signaling pathways . This binding triggers the expression of antiviral proteins, such as a protein kinase and an oligoadenylate synthetase, which inhibit viral RNA replication and enhance natural killer cell cytotoxicity against viruses. |
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