Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody proteintech 98017-1-RR

$77.00
In stock
SKU
98017-1-RR

 

CD276, B7-H3, B7H3, B7 homolog 3, B7 H3

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: CD276 molecule
 Applications: FC Observed Molecular Weight: NM_001024736
Formulation: PBS, Azide GenBank Accession Number: 80381
Conjugate: Unconjugated Gene Symbol: AB_3672161
Tested Applications: Positive FC detected in Gene ID (NCBI): Unconjugated
Application: Flow Cytometry (FC) RRID: Liquid
Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension Conjugate: Protein A purfication
Tested Reactivity: Human Form: Q5ZPR3
Host / Isotype: Recombinant Background Information: B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).

 

 

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