Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody proteintech 98017-1-RR
$77.00
In stock
SKU
98017-1-RR
CD276, B7-H3, B7H3, B7 homolog 3, B7 H3
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD276 molecule |
| Applications: FC | Observed Molecular Weight: NM_001024736 |
| Formulation: PBS, Azide | GenBank Accession Number: 80381 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672161 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: Q5ZPR3 |
| Host / Isotype: Recombinant | Background Information: B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063). |