Anti-Human FLT4/VEGFR3 Rabbit Recombinant Antibody proteintech 98633-1-RR
$119.00
In stock
SKU
98633-1-RR
FLT4, EC:2.7.10.1, FLT 4, FLT-4, FLT41
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: fms-related tyrosine kinase 4 |
| Applications: FC | Observed Molecular Weight: NM_182925 |
| Formulation: PBS, Azide | GenBank Accession Number: 2324 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: P35916-1 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: FLT4, also named VEGFR-3, belongs to the protein kinase superfamily, Tyr protein kinase family, and CSF-1/PDGF receptor subfamily. It is a receptor for VEGFC. FLT4 has a tyrosine-protein kinase activity. Defects in FLT4 cause lymphedema hereditary type 1 (LYH1A). Defects in FLT4 are found in juvenile hemangioma. VEGFR-3 is a highly glycosylated protein and migrates as bands with different molecular weights: an ~175 kDa precursor, an ~195 kDa mature form, an ~140 kDa non-glycosylated backbone, and a form that appears to be partially cleaved proteolytically in the extracellular domain to produce an ~125 kDa band(PMID: 15389531). |
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