Anti-Human Fas/CD95 Rabbit Recombinant Antibody proteintech 98034-1-RR
$111.00
In stock
SKU
98034-1-RR
FAS, APT1, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, APO-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: Human | Immunogen: Fas (TNF receptor superfamily, member 6) |
| Applications: FC | Observed Molecular Weight: NM_000043.6 |
| Formulation: PBS, Azide | GenBank Accession Number: 355 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672179 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P25445-1 |
| Host / Isotype: Recombinant | Background Information: FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
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